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Fig. 5 | Virology Journal

Fig. 5

From: Efficacy of recombinant H5 vaccines delivered in ovo or day of age in commercial broilers against the 2015 U.S. H5N2 clade 2.3.4.4c highly pathogenic avian Influenza virus

Fig. 5

Serum HI titers (log2) in broiler chicks immunized with recombinant vaccine and challenged with HPAI in experiment 1. G1, G2, G3: 18 d old embryonated eggs were vaccinated in ovo with PBS (Sham control; G1) or RP-H5 (G2) or rHVT-AI (G3). G4: Birds in G2 group were given an additional RP-H5 booster dose at 3 weeks of age (G4). G5: Day old birds were vaccinated with both rHVT-AI and RP-H5 vaccine. Birds were challenged with HPAI virus at either 3 weeks of age (Fig. 5A) or 6 weeks of age (Fig. 5B). Serum samples were taken on day 0 (Pre) and day 14 (Post) after challenge. Statistical differences are indicated by different lowercase lettering (P < 0.05)

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