Fig. 5From: Efficacy of recombinant H5 vaccines delivered in ovo or day of age in commercial broilers against the 2015 U.S. H5N2 clade 2.3.4.4c highly pathogenic avian Influenza virusSerum HI titers (log2) in broiler chicks immunized with recombinant vaccine and challenged with HPAI in experiment 1. G1, G2, G3: 18 d old embryonated eggs were vaccinated in ovo with PBS (Sham control; G1) or RP-H5 (G2) or rHVT-AI (G3). G4: Birds in G2 group were given an additional RP-H5 booster dose at 3 weeks of age (G4). G5: Day old birds were vaccinated with both rHVT-AI and RP-H5 vaccine. Birds were challenged with HPAI virus at either 3 weeks of age (Fig. 5A) or 6 weeks of age (Fig. 5B). Serum samples were taken on day 0 (Pre) and day 14 (Post) after challenge. Statistical differences are indicated by different lowercase lettering (P < 0.05)Back to article page