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Fig. 3 | Virology Journal

Fig. 3

From: Efficacy of recombinant H5 vaccines delivered in ovo or day of age in commercial broilers against the 2015 U.S. H5N2 clade 2.3.4.4c highly pathogenic avian Influenza virus

Fig. 3

Viral titers from oral swabs in broiler chicks immunized with recombinant vaccine and challenged with HPAI virus in experiment 1. G1, G2, G3: 18-day-old embryonated eggs were vaccinated in ovo with PBS (Sham control; G1) or RP-H5 (G2) or rHVT-AI (G3). G4: Birds in G2 group were given an additional RP-H5 booster dose subcutaneously at 3 weeks of age. G5: Day old birds were vaccinated with both rHVT-AI and RP-H5 vaccine. Birds were challenged with A/turkey/Minnesota/12,582/2015(H5N2) clade 2.3.4.4 HPAI virus at either 3 weeks of age (Fig. 3A) or 6 weeks of age (Fig. 3B). Swabs were analyzed at 2 and 4 dpc using qRRT-PCR. Viral titers are expressed as log10 EID50/ml. Statistical differences are indicated by different lowercase lettering (P < 0.05)

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Virology Journal

ISSN: 1743-422X