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Fig. 1 | Virology Journal

Fig. 1

From: Efficacy of recombinant H5 vaccines delivered in ovo or day of age in commercial broilers against the 2015 U.S. H5N2 clade 2.3.4.4c highly pathogenic avian Influenza virus

Fig. 1

Kaplan-Meier survival plots of broiler chicks immunized with recombinant vaccines and challenged with HPAI virus in experiment 1. Eighteen day-old embryonated eggs were vaccinated in ovo with PBS (G1), RP-H5 (G2), rHVT-AI (G3), RP-H5 in ovo and boost at 3 weeks of age (G4), or combined rHVT-AI and RP-H5 delivered subcutaneously SQ at one day-of-age (G5). Birds were challenged with A/turkey/Minnesota/12,582/2015 H5N2 clade 2.3.4.4c HPAI virus at either 3 weeks of age (Fig. 1A) or 6 weeks of age (Fig. 1B). Statistical differences in percent survival were determined using the Mantel-Cox log-rank test and indicated by different lowercase letters (P < 0.05)

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