Table 1 KEGG pathway significantly enriched
Pathway | KEGG Class | Pathway Name | Count | Background Number | P Value |
|---|---|---|---|---|---|
ko04060 | Environmental Information Processing; Signaling molecules and interaction | Cytokine-cytokine receptor interaction | 10 | 292 | 7.46 × 10− 4 |
ko04020 | Environmental Information Processing; Signal transduction | Calcium signaling pathway | 9 | 240 | 8.99 × 10− 4 |
ko04061 | Environmental Information Processing; Signaling molecules and interaction | Viral protein interaction with cytokine and cytokine receptor | 6 | 95 | 0.0012 |
ko05410 | Human Diseases; Cardiovascular disease | Hypertrophic cardiomyopathy | 5 | 91 | 0.0072 |
ko05414 | Human Diseases; Cardiovascular disease | Dilated cardiomyopathy | 5 | 94 | 0.008 |
ko00380 | Metabolism; Amino acid metabolism | Tryptophan metabolism | 4 | 52 | 0.0095 |
ko02010 | Environmental Information Processing; Membrane transport | ABC transporters | 4 | 52 | 0.0095 |
ko00982 | Metabolism; Xenobiotics biodegradation and metabolism | Drug metabolism - cytochrome P450 | 4 | 71 | 0.0219 |
ko04062 | Organismal Systems; Immune system | Chemokine signaling pathway | 6 | 192 | 0.0228 |
ko05412 | Human Diseases; Cardiovascular disease | Arrhythmogenic right ventricular cardiomyopathy | 4 | 77 | 0.0271 |
ko04510 | Cellular Processes; Cellular community - eukaryotes | Focal adhesion | 6 | 201 | 0.0272 |
ko04260 | Organismal Systems; Circulatory system | Cardiac muscle contraction | 4 | 87 | 0.0370 |
ko04024 | Environmental Information Processing; Signal transduction | cAMP signaling pathway | 6 | 220 | 0.0380 |
ko04512 | Environmental Information Processing; Signaling molecules and interaction | ECM-receptor interaction | 4 | 88 | 0.0381 |
ko00350 | Metabolism; Amino acid metabolism | Tyrosine metabolism | 3 | 40 | 0.0446 |