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Fig. 6 | Virology Journal

Fig. 6

From: Phillyrin ameliorates influenza a virus-induced pulmonary inflammation by antagonizing CXCR2 and inhibiting NLRP3 inflammasome activation

Fig. 6

The binding affinity between phillyrin and CXCR2. Interactions of CXCR2 with phillyrin measured by SPR. The CXCR2 with a his-Tag was fixed on the NTA sensor chip via capture coupling and serial dilutions of phillyrin (6.25µM, 12.5µM,25µM,50µM) were used as analytes. Changes in plasmon resonance are shown as response units. (a) Multicycle kinetics using CXCR2 as ligand and phillyrin as analyte. Different colored lines correspond to different concentrations of Phillyrin; (b)The KD value of phillyrin and CXCR2 was calculated by non-linear regression analysis

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Virology Journal

ISSN: 1743-422X