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Fig. 2 | Virology Journal

Fig. 2

From: DENV-2 NS1 promotes AMPK-LKB1 interaction to activate AMPK/ERK/mTOR signaling pathway to induce autophagy

Fig. 2

DENV-2 NS1 induces autophagy through AMPK/ERK/mTOR signaling pathway. A Protein immunoblotting was used to detect changes in the AMPK/ERK/mTOR signaling pathway and autophagy-related molecules in four groups of MOCK, DENV-2, Empty vector and NS1-OE. B Protein immunoblotting was used to detect changes in AMPK/ERK/mTOR signaling pathway and autophagy-related molecules in five groups of MOCK, Empty vector and NS1-OE, Dorsomorphin, Dorsomorphin + NS1-OE. *represents comparison with MOCK, *p < 0.05, **p < 0.01, ***p < 0.001; # represents comparison with Dorsomorphin + DENV-2 NS1-OE group, #p < 0.05, ##p < 0.01, ##p < 0.001

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