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Fig. 4 | Virology Journal

Fig. 4

From: Genome analysis of SARS-CoV-2 isolates from a population reveals the rapid selective sweep of a haplotype carrying many pre-existing and new mutations

Fig. 4

A proposed scheme for the evolution of the amino acid changes found in the 92 sequenced genomes in Assam. A A selective sweep and losses of variants. The amino acid changes are represented as in Fig. 3. A haplotype having a set of 13 underwent a selective sweep in Assam. B Sequential occurrences of frame-sift variants in the 92 SARS-CoV-2 genomes of Assam. Fifteen frame-shift variants (indicated by the black bar) arose sequentially and were added to the genomes at different time points. The tree is constructed by the Neighbour Joining (NJ) method using the presence and absence of variants in a particular genome as the distance measure. The basal variant represents the oldest variant that is fixed in the population of Assam. The frequencies of the variants and their occurrences in a particular gene are detailed in Fig. 3. * Frame-sift variant in a region of the genome not found in the GISAID databse

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Virology Journal

ISSN: 1743-422X