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Fig. 5 | Virology Journal

Fig. 5

From: Vaccinia virus induces endoplasmic reticulum stress and activates unfolded protein responses through the ATF6α transcription factor

Fig. 5

Regulation of ER stress target genes in wild-type MEFs or ATF6α deficient cells. Wild-type and ATF6α knockout MEFs were infected with MOI 10 or treated with 1 µg/mL tunicamycin. Total RNA was extracted and RT-qPCR analysis of relative mRNA contents for BiP/GRP78 (a), PDIA4 (b), CHOP (c), and total XBP-1 (d) were performed after cDNA synthesis. * or *** indicate statistical significant differences between groups (p < 0.05 or p < 0.001, respectively) as determined by ANOVA followed by Bonferroni’s test. Data were collected from three independent experiments. Results were plotted as mean ± SD

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Virology Journal

ISSN: 1743-422X