Table 2 Laboratory, biomarkers and cytokine pro-inflammatory panel
Blood count | Reference range | Acute phase | Recovery phase |
|---|---|---|---|
Hemoglobin (gr/dL) | 13.2–18.0 | 16.4 | - |
Hematocrit (%) | 38.4–52.4 | 46.7 | - |
Platelet count (x 10^3/uL) | 150.0-420.0 | 227 | - |
White-cell count (x 10^3/uL) | 4.5–11.0 | 6.7 | - |
Absolute neutrophil count (x 10^3/uL) | 2.5-7.0 | 4.1 | - |
Absolute lymphocyte count (x 10^3/uL) | 1.0–4.0 | 1.3 | - |
Absolute monocyte count (x 10^3/uL) | 0.2–1.2 | 1.0 | - |
Comprehensive Metabolic Panel | |||
Creatinine (mg/dL) | 0.7–1.3 | 1.1 | - |
Blood urea nitrogen (mg/dl) | 8.9–25.7 | 11.5 | - |
Lactate dehydrogenase (U/L) | 125.0-243.0 | 254 | - |
Inflammatory biomarkers | |||
C-reactive protein (mg/dL) | 0.0-0.5 | 5.51 | - |
Erythrocyte sedimentation rate (mm/hr) | 1–20 | 3.0 | - |
Procalcitonin (ng/mL) | < 0.5 | < 0.05 | - |
Cardiac biomarkers | |||
hs-c-TnI (ng/L) | 0.0-34.2 | 805.1 | - |
BNP (pg/mL) | < 100 | 30.1 | - |
D-Dimer (ng/mL) | < 243 | 54.0 | - |
Pro-inflammatory cytokine | Control group* | ||
IL-1β | 0.5 ± 1.3 | < 11.88 | < 11.88 |
IFN-α2 | 41.6 ± 106.5 | < 9.61 | < 9.61 |
IFN-γ | 1.7 ± 2.7 | < 17.33 | 34.43 |
TNF-α | 1.7 ± 3 | < 20.06 | < 20.06 |
MCP-1 | 0.1 ± 70.5 | 1220.2 ↑ | 764.4 ↑ |
IL-6 | 0.7 ± 0.9 | < 1.37 | 2.61 ↑ |
IL-8 | 1.5 ± 2.3 | 47.23 ↑ | < 5.37 |
IL-10 | 1.0 ± 1.4 | 24.74 ↑ | < 0.69 |
IL-12p70 | 0.6 ± 0.7 | < 0.06 | < 0.06 |
IL-17 A | 6.3 ± 20.2 | < 113.22 | < 113.22 |
IL-18 | 169.6 ± 94.2 | 2177.1 ↑ | 1516.7 ↑ |
IL-23 | 4.3 ± 8.8 | 5.30 | 5.30 |
IL-33 | 2.5 ± 3.4 | 4.6 ↑ | 2.6 |