Epidemiological change of influenza virus in hospitalized children with acute respiratory tract infection during 2014−2022 in Hubei Province, China

Table 1 The positive rate of IFV in the hospitalized children during January 2014 to June 2022

Group	No. of children (%)	Positive (%)			Positive rate (95% CI), %	OR (95% CI)	P
Group	No. of children (%)	Total	IFV-A	IFV-B	Positive rate (95% CI), %	OR (95% CI)	P
Overall	75,128	1486 (100)	954 (64.20)	521 (35.06)	1.98 (1.88–2.01)
Gender
Male	44,961 (59.85)	882 (59.35)	580 (60.80)	295 (56.62)	1.96 (1.84–2.10)	1.01 (0.91–1.12)	0.830^a
Female	30,167 (40.15)	604 (40.65)	374 (39.20)	226 (43.38)	2.00 (1.85–2.17)	Reference
Age, year
< 1	26,498 (35.27)	358 (24.09)	271 (28.41)	83 (15.93)	1.36 (1.22–1.50)	Reference
1–2	23,919 (31.84)	536 (36.07)	361 (37.84)	174 (33.40)	2.24 (2.06–2.44)	1.70 (1.48–1.95)	< 0.001^b
3–5	19,207 (25.57)	426 (28.67)	251 (26.31)	172 (33.01)	2.22 (2.01–2.44)	1.68 (1.46–1.94)	< 0.001^b
6–17	5504 (7.33)	166 (11.17)	71 (7.44)	92 (17.66)	3.02 (2.58–3.50)	2.32 (1.92–2.80)	< 0.001^b
Diagnosis
URTI	21,983 (29.26)	420 (28.26)	248 (26.00)	170 (32.63)	1.91 (1.73–2.10)	Reference
LRTI	53,145 (70.74)	1066 (71.74)	706 (74.00)	351 (67.37)	2.01 (1.89–2.13)	1.13 (1.01–1.27)	0.032^c

IFV Influenza virus, URTI, Upper respiratory tract infection, LRTI, Lower respiratory tract infection, CI, Confidence interval, OR, Odds ratio, P P value
^aAdjusted for gender and diagnosis
^bAdjusted for age and diagnosis
^cAdjusted for age and gender. There were 11 children mixed infection with IFV-A and IFV-B

ISSN: 1743-422X