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Table 7 Frequency of ACE2 Haplotypes distribution in COVID-19 patients: ATC and TTTGTAGTTAGTA were most common haplotypes found. ATC haplotypes found in 120 patients having 66 serious patients while TTTGTAGTTAGTA found in 112 patients with 64 serious patients

From: Angiotensin-converting enzyme 2 (ACE2) polymorphisms and susceptibility of severe SARS-CoV-2 in a subset of Pakistani population

Haplotype

Frequency

Severity

OR (95%: CI)

p-value

ATC

120 (69.77%)

Non-Serious (54; 43.54%)

Serious (66; 53.22%)

3.27 (1.10–9.70)

0.029*

TTTGTAGTTAGTA

112 (90.3%)

Non-Serious (48; 38.70%)

Serious (64; 51.61%)

5.44 (2.12–13.93)

< 0.001*

  1. OR, odds ratio; CI, confidence interval; *P < 0.05 was considered statistically significant
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Virology Journal

ISSN: 1743-422X