Table 6 Genotype distribution in COVID-19 severity groups disaggregated by age gender. rs2285666 had the positive association with gender with male dominance (69 patients), having the CC genotyping (21 patients)
ACE2 Single nucleotide variant | Gender | Severity | Genotype frequency | P | OR (CI 95%) | |||
|---|---|---|---|---|---|---|---|---|
CC | AA | CT | TT | |||||
rs2285666 | Male (n = 69) Female (n = 55) | Serious (n = 38) Non serious (n = 31) Serious (n = 30) Non serious (n = 25) | 21 (0.553) 19 (0.613) 11 (0.367) 10 (0.4) | 0 (0) 0 (0) 1 (0.034) 0 (0) | 0 (0) 1 (0.032) 2 (0.066) 3 (0.12) | 17 (0.447) 11 (0.355) 16 (0.533) 12 (0.48) | 0.034 | 1.438 (1.028–2.011) |