Table 5 Genotype distribution in COVID-19 severity groups disaggregated by age group. rs76888331 was found to have positive statistical association with the age having the 95 patients with age > 50 years, serious (53 patients) with TT genotyping (53 patients)
ACE2 Single nucleotide variant | Age Group | Severity | Genotype frequency | P | OR (CI 95%) | ||
|---|---|---|---|---|---|---|---|
CC | AA | TT | |||||
rs768883316 | < =50 Years (n = 29) > 50 Years (n = 95) | Serious (n = 15) Non serious (n = 14) Serious (n = 53) Non serious (n = 42) | 0 (0) 0 (0) 0 (0) 2 (0.048) | 4 (0.266) 0 (0) 0 (0) 1 (0.024) | 11 (0.734) 14 (1.00) 53 (1.00) 39 (0.928) | 0.026 | 1.953 (1.085–3.514) |