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Fig. 4 | Virology Journal

Fig. 4

From: Flexible upscaling of laboratory PCR testing capacity at the Robert Koch Institute during the SARS-CoV-2 pandemic

Fig. 4

Overview of sample pooling parameters. Depending on the percentage of positive samples (prevalence), the mean percentage of positive pools and the mean percentage of saved tests compared to individual testing is listed for pool sizes of two to ten samples. The color code refers to the percentage of saved tests. The blue curve shows the theoretical increase of the Ct value compared to individual testing for each pool size \(\begin{aligned} {\text{Calculations}}: & {\text{Percentage of positive pools}} = 1 - (1 - {\text{prevalence}}){\mathrm{pool size}} \\ & {\text{Percentage of saved tests}} = (1 - {\text{prevalence}}){\text{pool size}} - 1/{\text{pool size}}. \\ \end{aligned}\)

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