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Fig. 5 | Virology Journal

Fig. 5

From: Linear epitopes on the capsid protein of norovirus commonly elicit high antibody response among past-infected individuals

Fig. 5

VLP-HBGA binding antibody blockade assay. A Spatial structure of the VP1 protein and locations of linear epitopes. B Schematic of immunizing mice with epitope-KLH conjugation by Figdraw. C The titer of antiserum was detected by peptide ELISA. The control group was normal mouse serum immunized with NaCl and adjuvant. D Diagram of VLP-carbohydrate binding blockade assay by Figdraw. E The blocking efficiency of the antiserum, with normal mouse serum as the negative control and the Anti-Norovirus GII.4 (Absolute Antibody, NVB43.9) which have a block function as the positive control; mixed serum is a mixture of two epitope antisera

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