Fig. 2

Mapping linear B-cell epitopes of VP1 and VP2. A VP1 and B VP2 of the heatmap for screening linear B-cell epitopes identified in 20 double-positive subjects. The individual's specific IgG responses to 9 matrix pools and corresponding peptides were detected. For each individual, the highest IgG response to one pool or peptide in a pool was noted as "1" and considered as high response (HR), filled with a dark red mark, the other responses were evaluated by their relative strength against HR. The responses with strength between 81 and 99% of the HR was considered as a sub-high response and was marked in red. Total responses (TR) included all highest and sub-high responses. C Domain, sites and amino acid sequence information of all linear epitopes