Fig. 2
From: Cross-reactive immune responses to monkeypox virus induced by MVA vaccination in mice
MVA-induced neutralizing antibodies against MVA or MPXV. BALB/c mice (n = 5) were immunized twice with different MVA concentrations. (A) On day 42 postimmunization, the neutralizing antibody titers against MVA virus induced by MVA were determined by PRNT with 100 TCID50 MVA virus on BHK-21 cells. (B) On day 42 postimmunization, the neutralizing antibody titers against MPXV induced by MVA concentration of 107 TCID50/mL were determined by PRNT with 600 pfu MPXV on Vero cells. Comparing the vaccination effect among MVA and PBS groups, the asterisk * indicates a significant difference (P < 0.05) detected by one-way ANOVA or T-test analysis.