Table 1 Activity index of selected compounds
From: Identification of small molecules capable of enhancing viral membrane fusion
Fusion % at CC50 | Activity index (Fusion % at CC50/CC50) | ||||
|---|---|---|---|---|---|
CC50 (µM) | NO TMPRSS2 | TMPRSS2 | NO TMPRSS2 | TMPRSS2 | |
Latanoprost | 63,86 | 70,98 | 152,75 | 1,11 | 2,39 |
Diperodon | 40,96 | 123,98 | 138,77 | 3,03 | 3,39 |
Ethynylestradiol | 49,89 | 162,00 | 312,60 | 3,25 | 6,27 |
Simvastatin | 34,17 | 172,00 | 163,57 | 5,03 | 4,79 |
Rabeprazol | 38,08 | 179,16 | 243,51 | 4,70 | 6,39 |
Ethaverine | 43,84 | 125,39 | 419,22 | 2,86 | 9,56 |