Table 4 Comparative analysis of inflammatory cytokines between Omicron variants ∆872 BA.2 breakthrough infected adolescents and adults
Variables (median [IQR]) | Normal reference range | Adolescents (n = 21) | Adults (n = 7) | p-value |
|---|---|---|---|---|
CRP | 0–8.2 | 8.02(5.02–12.92) | 2.95(1.26–4.51) | 0.019 |
IL-2 |  ≤ 11.4 | 0.9(0.69–1.52) | 1.23(0.79–2.06) | 0.473 |
IL-4 |  ≤ 12.9 | 2.16(1.65–2.63) | 2.39(1.49–3.01) | 0.668 |
IL-6 |  ≤ 20.0 | 3.83(3.3–4.59) | 4.72(4.08–8.56) | 0.056 |
IL-10 |  ≤ 5.9 | 2.36(1.86–3.38) | 3.18(1.94–3.89) | 0.368 |
TNF-α |  ≤ 5.5 | 1.99(1.6–2.32) | 2.07(1.83–2.75) | 0.370 |
IFN-γ |  ≤ 17.3 | 2.32(1.82–2.64) | 2.22(1.73–2.86) | 0.896 |
IL-17A |  ≤ 20.6 | 5.54(3.33–2.48) | 3.52(2.0–4.31) | 0.104 |
IL1-β |  ≤ 12.1 | 1.27(0.91–2.26) | 1.52(1.15–1.91) | 0.907 |
IL-5 |  ≤ 3.4 | 0.59(0.45–0.9) | 0.73(0.49–0.97) | 0.275 |
IL-12P70 |  ≤ 3.2 | 1.86(1.4–2.33) | 1.86(1.11–2.01) | 0.440 |
IFN-α |  ≤ 7.9 | 4.74(2.47–11.48) | 3.67(1.62–18.11) | 0.928 |
IL-8 |  ≤ 21.4 | 2.87(1.33–7.66) | 10.26(7.18–29.53) | 0.002 |