Table 2 Baseline characteristics of enrolled Omicron variants ∆872 BA.2 and WT BA.2 breakthrough infected adult patients

Age (years)

35(31–45)

43(36–56)

0.381

Sex

 Female

15(37.5%)

5(71.4%)

0.094

 Male

25(62.5%)

2(28.6%)

Vaccination status

 Two doses of InV

19(47.5%)

2(28.6%)

0.353

 Three doses of InV

21(52.5%)

5(71.4%)

Hospital stay days

13(9.75–15)

7(6–9)

0.020

CT value(NP)

17.0(15.0–20.0)

19.43(18.66–23.20)

0.070

CT value(ORF1ab)

17.0(14.0–20.89)

19.52(17.46–24.28)

0.256

Symptoms

 Fever

32(80%)

5(71.4%)

0.898

 Sore throat

13(32.5%)

2(28.6%)

 Cough

21(52.5%)

4(57.1%)

 Fatigue

13(32.5%)

1(14.3%)

 Headaches

12(30%)

1(14.3%)

 Diarrhea

8(20%)

0

 Stuffy nose

7(17.5%)

1(14.3%)

 Myalgia

2(5%)

1(14.3%)

 Nausea and vomiting

1(2.5%)

0

Severity

 Asymptomatic

18(45%)

1(14.3%)

0.047

 Mild

22(55%)

6(85.7%)

Underlying diseases

 Cardiovascular diseases

3(7.5%)

0

0.405

 Hypertension

1(2.5%)

1(14.29%)

 Pulmonary inflammation

1(2.5%)

0

 Pulmonary bulla

1(2.5%)

0

Complete blood counts

 WBC(10⁹/L)

5.81(4.41–8.45)

6.23(5.94–7.83)

0.512

 RBC(10¹²/L)

4.89(4.60–5.29)

4.49(4.29–4.90)

0.086

 HGB(g/L)

140.0(125.8–149.0)

134.0(129.0–157.0)

0.725

 Platelet(10⁹/L)

260.0(225.5–306.3)

203.0(193.0–232.0)

0.041

 Neutrophils(10⁹/L)

4.05(3.06–6.56)

4.69(4.29–5.54)

0.827

 Monocytes(10⁹/L)

0.48(0.335–0.58)

0.49(0.41–0.71)

0.386

 Lymphocyte(10⁹/L)

1.06(0.75–1.48)

0.93(0.52–1.51)

0.582

 Eosinophils(10⁹/L)

0.04(0.01–0.09)

0.12(0.07–0.18)

0.027

 Basophils(10⁹/L)

0.01(0.01–0.01)

0.01(0–0.01)

0.280