Table 1 Titers of the WHO IS for HBV DNA quantified by HBV DNA kits
DNA-IS | DNA-IS 1 | DNA-IS 2 | DNA- IS 3 | DNA- IS 4 | DNA- IS 5 | DNA- IS 6 | DNA- IS 7 | |
|---|---|---|---|---|---|---|---|---|
Theoretical titer (log IU/mL) | 4.0 | 3.5 | 3.0 | 2.5 | 2.0 | 1.5 | 1.0 | |
ART HBV | Titer (log IU/mL) | 3.85 | 3.39 | 2.94 | 2.45 | 2.05 | 1.77 | 1.19 |
CV (%) | 3.75 | 3.14 | 2.00 | 2.00 | 2.50 | 18.0 | 19.0 | |
Alinity HBV | Titer (log IU/mL) | 3.99 | 3.52 | 3.11 | 2.62 | 2.26 | 1.56 | 1.34 |
CV (%) | 0.25 | 0.57 | 3.67 | 4.80 | 13.0 | 4.00 | 34.0 | |
CAP/CTM HBV v2.0 | Titer (log IU/mL) | 4.03 | 3.53 | 3.00 | 2.43 | 2.11 | 1.46 | < 1.30 |
CV (%) | 0.75 | 0.86 | 0.00 | 2.80 | 5.50 | 2.67 | ND | |
Cobas HBV | Titer (log IU/mL) | 3.92 | 3.41 | 2.93 | 2.47 | 1.99 | 1.49 | 1.09 |
CV (%) | 2.00 | 2.57 | 2.33 | 1.20 | 0.50 | 0.67 | 9.00 | |
Aptima HBV | Titer (log IU/mL) | 4.04 | 3.57 | 3.11 | 2.56 | 2.30 | 1.51 | 1.20 |
CV (%) | 1.00 | 2.00 | 3.67 | 2.40 | 15.0 | 0.67 | 20.0 | |