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Table 1 Selected PML NB protein partners and their functions

From: The interactions between PML nuclear bodies and small and medium size DNA viruses

Name

Main function (reviewed in)

Discovered as PML NBs partner in:

Sp100, Sp110

Recognition of histone post-translational modifications, regulation of gene expression [18, 19]

[7, 20,21,22]

Daxx

Apoptosis, regulation of transcription, H3.3 chaperone [23, 24]

[25, 26]

ATRX

Chromatin remodeling, H3.3 chaperone [27]

[28]

H3.3

Regulation of transcription [17]

[29]

MRE11 complex

Maintenance of genome stability, response to DNA damage [30]

[31, 32]

p53

Cell cycle regulation, tumor growth suppression, pro-apoptotic transcription factor [33]

[34,35,36,37]

HP1

Heterochromatin formation [38]

[39]

SMC5/6

Maintenance of chromatin structure, DNA repair [40]

[41]

HDAC1

Histone deacetylase [42]

[43]

S100A10 (P11)

Maintenance of calcium homeostasis and transduction pathway signaling [44]

[45]

ZNF198

Chromatin remodeling [46]

[47]

SUZ12

Chromatin remodeling [48]

[49]

FOXO4

Transcription factor [50]

[51]