From: The interactions between PML nuclear bodies and small and medium size DNA viruses
Name | Main function (reviewed in) | Discovered as PML NBs partner in: |
---|---|---|
Sp100, Sp110 | Recognition of histone post-translational modifications, regulation of gene expression [18, 19] | |
Daxx | Apoptosis, regulation of transcription, H3.3 chaperone [23, 24] | |
ATRX | Chromatin remodeling, H3.3 chaperone [27] | [28] |
H3.3 | Regulation of transcription [17] | [29] |
MRE11 complex | Maintenance of genome stability, response to DNA damage [30] | |
p53 | Cell cycle regulation, tumor growth suppression, pro-apoptotic transcription factor [33] | |
HP1 | Heterochromatin formation [38] | [39] |
SMC5/6 | Maintenance of chromatin structure, DNA repair [40] | [41] |
HDAC1 | Histone deacetylase [42] | [43] |
S100A10 (P11) | Maintenance of calcium homeostasis and transduction pathway signaling [44] | [45] |
ZNF198 | Chromatin remodeling [46] | [47] |
SUZ12 | Chromatin remodeling [48] | [49] |
FOXO4 | Transcription factor [50] | [51] |