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Table 3 Effect of different variables on clearance of HPV infection after treatment in women with HSIL or worse lesions

From: Peripheral blood lymphocytes influence human papillomavirus infection and clearance: a retrospective cohort study

variables

HPV Clearance (Univariate)

 

HPV Clearance (Multivariate)

P(Unadjusted)

HR(Unadjusted)

95%CI

C-index

 

P(Adjusted)

HR(Adjusted)

95%CI

C-index

Age in years

0.02*

0.98

0.96-1.00

0.54

     

Gravidity

0.60

0.96

0.83–1.11

0.51

     

Parity

0.04*

0.81

0.66–0.99

0.57

     

Menopause

         

No

         

Yes

0.04*

0.58

0.34–0.98

0.55

     

B Cells

0.09

1.04

0.99–1.09

0.56

 

0.07

1.04

1.00-1.09

0.62

T Cells

0.41

0.99

0.96–1.02

0.51

 

0.12

0.98

0.95–1.01

0.59

CD4 + T Cells

0.42

0.98

0.95–1.02

0.52

 

0.82

1.01

0.96–1.05

0.59

CD8 + T Cells

0.53

0.99

0.96–1.02

0.48

 

0.09

0.97

0.95-1.00

0.60

NK Cells

0.82

1.00

0.97–1.03

0.52

 

0.63

1.01

0.98–1.04

0.58

CD4/CD8

0.49

0.90

0.67–1.21

0.52

 

0.63

1.09

0.77–1.54

0.58

  1. Calculated by univariate and multivariate Cox regression
  2. Multivariate Cox regression analysis was adjusted for age, gravidity, parity, and menopause
  3. C-index: concordance index
  4. HSIL: high-grade squamous intraepithelial lesion
  5. * Statistically significant at p < 0.05
  6.  HR: hazard ratio
  7. CI: confidence interval
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Virology Journal

ISSN: 1743-422X