Table 1 The epidemiology and pathogen distribution of HFMD cases in Beijing, China, 2009–2019
From: Molecular epidemiology and phylodynamic analysis of enterovirus 71 in Beijing, China, 2009–2019
Year | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 |
|---|---|---|---|---|---|---|---|---|---|---|---|
Case Number | 24,264 | 45,385 | 30,843 | 38,528 | 33,144 | 47,440 | 28,677 | 30,240 | 19,987 | 32,670 | 17,357 |
Population (/104) | 1972 | 1961.2 | 2018.4 | 2069.3 | 2114.8 | 2151.6 | 2170.5 | 2172.9 | 2170.7 | 2154.2 | 2153.6 |
Incidence rate (/105) | 123.0 | 231.4 | 152.8 | 186.2 | 156.7 | 220.5 | 132.1 | 139.2 | 92.1 | 151.7 | 80.6 |
Male (%) | 14,826 (61.1) | 27,372 (60.3) | 18,474 (59.9) | 23,079 (59.9) | 20,392 (61.5) | 27,992 (59.0) | 17,042 (59.4) | 17,770 (58.8) | 11,955 (59.8) | 19,460 (59.6) | 10,224 (58.9) |
Agea | 2.8 (1.8–3.9) | 3.0 (2.0–4.2) | 3.1 (2.0–4.2) | 3.3 (2.0–4.5) | 3.0 (1.6–4.4) | 3.3 (2.0–4.6) | 3.2 (1.8–4.5) | 3.5 (2.1–4.8) | 3.6 (2.1–5.2) | 3.5 (1.7–5.1) | 3.9 (2.3–5.9) |
Fatal cases (‰) | 4 (0.2) | 18 (0.4) | 5 (0.2) | 4 (0.1) | 2 (0.1) | 2 (0.0) | 1(0.0) | 0(0.0) | 0(0.0) | 0(0.0) | 0(0.0) |
Severe cases (%) | 104 (0.4) | 610 (1.3) | 278 (0.9) | 356 (0.9) | 152 (0.5) | 111(0.2) | 50(0.17) | 55(0.18) | 32(0.16) | 45(0.14) | 7(0.04) |
Etiology examination (n) | 1769 | 4174 | 3179 | 4791 | 2943 | 2570 | 1537 | 1979 | 1799 | 2671 | 1884 |
EV Positive sample (n) | 1204 | 2285 | 1508 | 2194 | 1762 | 1636 | 1114 | 1390 | 1222 | 2073 | 1450 |
EV71 (%) | 420(34.9) | 950(41.6) | 608(40.3) | 738(33.6) | 458(26.0) | 616(37.6) | 137(12.3) | 334(24.0) | 244(20.0) | 34(1.6) | 16(1.1) |
CVA16 (%) | 634(52.7) | 716(31.3) | 666(44.2) | 1191(54.3) | 519(29.5) | 729(44.6) | 338(30.3) | 624(44.9) | 189(15.5) | 377(18.2) | 613(42.3) |
Other EVd (%) | 150(12.5) | 602(26.3) | 223(14.8) | 233(10.6) | 870(49.4) | 290(17.7) | 643(57.7) | 433(31.2) | 788(64.5) | 1659(80.0) | 821(56.6) |
CVA6 (%) | NA | NA | NA | NA | 623(35.4) | 50(3.1) | 446(40.0) | 311(22.4) | 593(48.5) | 1238(59.7) | 605(41.7) |