Impaired antibody responses were observed in patients with type 2 diabetes mellitus after receiving the inactivated COVID-19 vaccines

Table 3 Multiple linear regression analysis for anti-RBD-IgG in T2DM patients

Variables	β	95% CI	P value
Age	− 0.343	(1.000, 0.012)	0.120
Sex (female)	0.608	(1.113, 3.692)	0.001
BMI	− 0.528	(− 0.625, − 0.142)	0.003
FPG	− 0.144	(− 0.375, 0.170)	0.443
HbA1c	− 0.154	(− 0.476, 0.195)	0.393
Insulin (use)	0.032	(− 1.476, 1.731)	0.870
Days after full-course vaccination	− 0.419	(− 0.047, − 0.006)	0.013
Other independent chronic diseases (with)	− 0.075	(− 1.524, 0.961)	0.642
Albumin	0.214	(− 0.023, 0.132)	0.158
Creatinine	0.038	(− 0.005, 0.007)	0.807

BMI body mass index, FPG Fasting Plasma Glucose, HbA1c Hemoglobin A1c, CI confidential interval, β standard regression coefficient, D–W Durbin–Waston: 1.926
p < 0.05 was considered statistically significant

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