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Table 4 The relation between HHV-6 viral load and clinical or biological manifestations potentially related to HHV-6 in HHV-6 DNAemia positive patients

From: Human herpesvirus-6 in hematopoietic stem cell transplant recipients: a prospective cohort study in Egypt

 

Viral load

Test of significance

p

< 104

(n = 10)

> 104

(n = 5)

No

%

No

%

Unexplained fever

5

50.0

1

20.0

χ2 = 1.250

FEp = 0.580

Cutaneous rash

0

0.0

2

40.0

χ2 = 4.615

FEp = 0.095

Pneumonitis

0

0.0

2

40.0

χ2 = 4.615

FEp = 0.095

aGVHD

1

10.0

0

0.0

χ2 = 0.536

FEp = 1.000

Thrombocytopenia

3

30.0

2

40.0

χ2 = 0.150

FEp = 1.000

Delayed engraftment/bone marrow suppression

4

40.0

2

40.0

χ2 = 0.000

FEp = 1.000

Days to platelets engraftment (mean)

      

 Mean ± SD.(Range)

10.60 ± 1.58 (8.0–13.0)

 

11.20 ± 1.79 (9.0–13.0)

 

t = 0.666

0.517

 Median (IQR)

10.50 (10–11)

 

11.0 (10–13)

   

Days to neutrophils engraftment (mean)

      

 Mean ± SD.(Range)

14.80 ± 5.90 (10.0–28.0)

 

11.80 ± 2.68 (9.0–16.0)

 

t = 1.067

0.305

 Median (IQR)

13.50 (10–17)

 

12.0 (10–12)

   
  1. HHV-6 human herpes virus-6, aGVHD acute graft versus host disease, CMV cytomegalovirus
  2. χ2: Chi square test, FE: Fisher Exact, t: Student t-test
  3. p: p value for comparing between negative and positive HHV-6 DNAemia