Fig. 4
From: Enterovirus B types cause severe infection in infants aged 0–3 months
Recombination analysis of E11 genomes in Guangzhou, China during January–December 2019. a Heatmap representation of evolutionary divergences between 64 reference strains and 5 E11 strains (MW883610–MW883614) obtained. Scale bars indicate the number of nucleotide substitutions per site, and bootstrap values were calculated on 1000 replicates. Red squares show positive correlation, and blue squares show negative correlation across the different regions of E6 and E11. b Similarity plot analysis comparing the 5 E11 strains (MW883610–MW883614), obtained in this study, with other closely related EV-B reference strains using Simplot software version 3.5.1 with a window size of 500 nt and step size of 20 bp. c Bootscan analysis comparing 5 E11 strains (MW883610–MW883614) obtained in this study with other closely related EV-B reference strains, using a window size of 500 nt and step size of 20 bp, and genetic distance of the Kirmura 2-parameter model. The arbitrary recombinant threshold was 70%