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Fig. 5 | Virology Journal

Fig. 5

From: Single-dose rAAV5-based vaccine provides long-term protective immunity against SARS-CoV-2 and its variants

Fig. 5

Protective effect of the ssAAV5-RBD-plus vaccine one-year post-immunization on various variants. A NA titers of wild-type (WT), Alpha, Beta SARS-COV-2; B Body weight of mice increased steadily. Immune antigenicity of ssAAV5-based and scAAV5-based vaccines in BALB/c mice; C IgG and D wild-type virus-specific NAs were evaluated at 40 days; E Among all doses of scAAV5-RBD-plus (1 × 1011, 1 × 1010, 5 × 109 and 1 × 109 GCs), 1 × 1011 GCs produced the highest IgG and NAs levels (F).

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Virology Journal

ISSN: 1743-422X