Fig. 7From: Tripartite motif-containing protein 46 accelerates influenza A H7N9 virus infection by promoting K48-linked ubiquitination of TBK1Schematic model of TRIM46-mediated K48-linked ubiquitination of TBK1. During avian influenza H7N9 virus infection, TRIM46 increased and interacted with TBK1. Then, TRIM46 mediated K48-linked ubiquitination of TBK1 and degraded TBK1, subsequently, decreased the phosphorylation of IRF3 and type I IFNs expressionBack to article page