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Fig. 4 | Virology Journal

Fig. 4

From: Molecular characteristics of a coxsackievirus A12 strain in Zhejiang of China, 2019

Fig. 4

a Simplot of general recombination identified in P2 region of the full-length coxsackievirus A12 (CV-A12) genome PJ201984 isolated in the study, as compared to CV-A12 strains and other enterovirus A (EV-A) prototype strains (prototype subset within the dataset 1), by using SimPlot. In the legend, “CVA12” indicated the combined group of all CV-A12 sequences retrieved in GenBank except CV-A12 prototype strain Texas-12; “CVA12ref” was Texas-12. b Recombination detection plot of PJ201984 by using RDP4. The breakpoint was 3302 nucleotide site in the complete coding sequence of PJ201984. c Simplot (1) and bootscan plot (2) performed in BLAST subset within the dataset 1, by using SimPlot. The bootscan analysis predicted that the recombination occurred between PJ201984 and a coxsackievirus A5 (CV-A5) strain isolated in 2017 in China (GenBank accession number MW079817). In the legend, “CVA12” indicated the combined group of all CV-A12 sequences retrieved in GenBank except CV-A12 prototype strain Texas-12; “CVA12ref” was Texas-12

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