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Fig. 1 | Virology Journal

Fig. 1

From: Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence

Fig. 1

The scatter charts present country specific CMV prevalence (mean) plotted against estimated age-standardized (world) annual incidence rates (per 100,000) of microscopically verified cases of B-cell types of cancer in 74 countries (blue circles) [35, 36, 69]. A) B-cell malignancies (all types) (Spearman ρ = -0.625, p < 0.001), B) Hodgkin’s disease (Spearman ρ = -0.618, p < 0.001), C) non-Hodgkin lymphomas (Spearman ρ =  = -0.617, p < 0.001), and D) multiple myeloma (Spearman ρ = -0.633, p < 0.001) in 2020. The inverse relationship between viral pervasiveness and the annual incidence rate of hematologic malignancies is highly significant for all (A) and each individual B-cell cancer type (C-D)

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Virology Journal

ISSN: 1743-422X