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Fig. 1 | Virology Journal

Fig. 1

From: Case report: BA.1 subvariant showing a BA.2-like pattern using a variant-specific PCR assay due to a single point mutation downstream the spike 69/70 deletion

Fig. 1

BA.2-like result of the cluster BA.1 + C21772T in the Fluorotype SARS-CoV-2 varIDQ (Hain Lifescience). Left: Melting curve for a representative sample of the cluster BA.1 + C21772T. Right: Melting curves for BA.1, BA.2, BA.4/5 and positive control samples. For all cases, the result given by the interpretation algorithm is shown on the bottom right of each melting curve plot. BA.1 gives a positive result in A67V + 69/70del, while BA.4/5 gives a positive result in 69/70del, as expected. The mutation C21772T in the BA.1 subvariant leads to the removal of the melting peak and a pattern similar to the BA.2 subvariant. The algorithm interprets the result of the BA.1 + C21772T samples as negative for both A67V-69/70del and 69/70del

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Virology Journal

ISSN: 1743-422X