Table 4 Factors associated with transmission within clusters
From: Transmission networks of hepatitis C virus among HIV/HCV-coinfected patients in Guangdong, China
Characteristics | Within transmission network, n = 133 (n/N, %) | Total sequences, N = 302 | P for fisher exact tests | OR (95% CI) | P–value | Adjusted OR (95% CI) | P–value |
|---|---|---|---|---|---|---|---|
Sex | |||||||
Male | 103 (42.92) | 240 | 0.475 | 1.000 | Â | Â | Â |
Female | 30 (48.39) | 62 |  | 1.247 (0.712–2.183) | 0.440 |  |  |
Age (years) | |||||||
 < 30 years | 7 (58.33) | 12 | 0.889 | 1.000 |  |  |  |
30–39 | 55 (43.31) | 127 |  | 0.546 (0.164–1.812) | 0.322 |  |  |
40–49 | 57 (44.19) | 129 |  | 0.565 (0.170–1.876) | 0.351 |  |  |
50–59 | 13 (43.33) | 30 |  | 0.516 (0.134–1.993) | 0.337 |  |  |
 >  = 60 | 1 (33.33) | 3 |  | 0.357 (0.025–5.109) | 0.448 |  |  |
Transmission routes | |||||||
Injecting drug use | 91 (45.73) | 199 | 0.681 | 1.000 | Â | Â | Â |
Heterosexual | 38 (40.00) | 95 |  | 0.791 (0.482–1.300) | 0.355 |  |  |
MSM | 2 (66.67) | 3 |  | 2.374 (0.212–26.603) | 0.483 |  |  |
Blood | 2 (40.00) | 5 |  | 0.791 (0.129–4.839) | 0.800 |  |  |
Marital status | |||||||
Unmarried | 39 (57.35) | 68 | 0.260 | 1.000 | Â | 1.000 | Â |
Married or cohabiting | 84 (40.00) | 210 |  | 0.496 (0.285–0.863) | 0.013 | 0.496 (0.285–0.863) | 0.013 |
divorced or separated | 5 (31.25) | 16 |  | 0.338 (0.106–1.080) | 0.067 | 0.338 (0.106–1.080) | 0.067 |
Widowed | 5 (71.43) | 7 |  | 1.859 (0.337–10.266) | 0.477 | 1.859 (0.337–10.266) | 0.477 |
unknown | 0 (0.00) | 1 |  | – | – | – | – |
Geographical region | |||||||
Pearl River Delta | 69 (40.35) | 171 | 0.419 | 1.000 | Â | Â | Â |
Eastern | 6 (60.00) | 10 |  | 2.217 (0.603–8.149) | 0.230 |  |  |
Western | 49 (48.51) | 101 |  | 1.393 (0.849–2.287) | 0.190 |  |  |
Northern | 9 (45.00) | 20 |  | 1.209 (0.476–3.073) | 0.689 |  |  |
Baseline CD4+T cell count (cells/mm3) | |||||||
 < 200 | 104 (45.41) | 229 | 0.852 | 1.000 |  |  |  |
200–349 | 25 (39.68) | 63 |  | 0.791 (0.448–1.395) | 0.418 |  |  |
350–499 | 3 (37.50) | 8 |  | 0.721 (0.168–3.089) | 0.660 |  |  |
 > 500 | 1 (50.00) | 2 |  | 1.202 (0.074–19.451) | 0.897 |  |  |
Subgenotypes | |||||||
1a | 2 (18.18) | 11 | 0.282 | 1.000 | Â | Â | Â |
1b | 27 (48.21) | 56 |  | 4.190 (0.830–21.157) | 0.083 |  |  |
2a | 0 (0.00) | 3 |  | – | – |  |  |
3a | 14 (42.42) | 33 |  | 3.316 (0.618–17.800) | 0.162 |  |  |
3b | 11 (52.38) | 21 |  | 4.950 (0.856–28.635) | 0.074 |  |  |
6a | 79 (44.89) | 176 |  | 3.665 (0.770–17.453) | 0.103 |  |  |
6n | 0 (0.00) | 2 |  | – | – |  |  |