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Table 3 Progression rate, odds ratio and p-value of CIN2 patients at 24 months of follow-up according to p16 and E6/E7mRNA

From: Possible role of negative human papillomavirus E6/E7 mRNA as a predictor of regression of cervical intraepithelial neoplasia 2 lesions in hr-HPV positive women

CIN2 Progression

Test

n°

n (%)

Odds Ratio (95% CI)

p-value

 

128

45 (35.1)

  

p16

negative

31

3 (9.7)

0.14 (0.04–0.49)

0.0006

positive

97

42 (43.3)

7.13 (2.03–25.04)

0.0006

E6/E7mRNA

negative

28

0

0.04 (0.01–0.33)

0.0001

positive

100

45 (45)

22.91 (3.00–175.00)

0.0001

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Virology Journal

ISSN: 1743-422X