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Table 1 Summery of peak values and time points of SARS-CoV-2 non-VOC and VOC replication kinetics in Vero E6, Caco-2, and Calu-3

From: Replication kinetics and infectivity of SARS-CoV-2 variants of concern in common cell culture models

  Max RNA level [copy number/mL] Time point of max RNA level [h p.i.] Max viral infectious titer [TCID50/mL] Time point of max viral infectious titer [h p.i.] Time point of visible CPE [h p.i.]
Vero E6      
Non-VOC 2.85E+09 96 9.17E+07 56 56
Alpha 1.70E+09 96 1.33E+07 72 56
Beta 2.98E+09 96 3.43E+06 80 80
Gamma 2.20E+09 96 2.40E+07 56 56
Delta 2.11E+09 96 3.63E+06 72 56
Omicron 2.14E+09 96 6.30E+05 96 72
Caco-2      
Non-VOC 4.36E+08 96 2.29E+07 96
Alpha 4.33E+08 96 1.08E+06 96
Beta 1.85E+08 96 1.52E+05 96
Gamma 9.30E+08 96 2.06E+06 96
Delta 5.86E++08 96 7.87E+05 72
Omicron 8.20E+05 96 3.54E+02 96
Calu-3      
Non-VOC 2.60E+08 96 1.20E+07 80 80
Alpha 1.24E+09 96 5.57E+06 96 72
Beta 1.07E+08 96 1.12E+06 80 96
Gamma 2.67E+09 96 5.16E+06 96 56
Delta 2.48E+09 96 1.98E+06 80 56
Omicron 1.28E+09 96 4.27E+06 96 80
  1. Max, maximum; h p.i., hours post infection; CPE, cytopathic effect