Table 3 Genotype distribution in COVID-19 patients and healthy controls
SNP | Subjects (n) | Genotype frequencies (%) | Pa | OR; 95% CI | Pc | OR; 95% CI | ||
|---|---|---|---|---|---|---|---|---|
GG | GA | AA | ||||||
A2350G | Negative control (n = 50) | 8 (16) | 20 (40) | 22 (44) | 0.010 | 4.7; 1.4–15.1 | 0.040 | 2.6; 1.1–6.3 |
Positive control (n = 35) | 11 (31.5) | 14 (40) | 10 (28.5) |  |  |  |  | |
ICU-admitted patients (n = 44) | 15 (34.1) | 19 (43.2) | 10 (22.7) |  |  |  |  | |
G8790A | Negative control (n = 50) | 24 (48) | 19 (38) | 7 (14) | 0.044 | 6.2; 1.1–35.7 | 0.0001 | 5.5; 2.4–12.4 |
Positive control (n = 35) | 28 (80) | 6 (17.2) | 1 (2.8) |  |  |  |  | |
ICU-admitted patients (n = 44) | 38 (86.3) | 5 (11.4) | 1 (2.3) |  |  |  |  | |