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Table 2 Linear regression analysis for factors associated with sPD-1 levels

From: The association between sPD-1 levels versus liver biochemistry and viral markers in chronic hepatitis B patients: a comparative study of different sPD-1 assays

Variables

sPD-1 by MyBioSource, log10 pg/mL

sPD-1 by R&D, log10 pg/mL

Univariate

Multivariate

Univariate

Multivariate

β coefficient (95% CI)

P value

β coefficient (95% CI)

P value

β coefficient (95% CI)

P value

β coefficient (95% CI)

P value

Gender (male vs. female)

0.001 (− 0.097–0.099)

0.9791

− 0.044 (− 0.107–0.020)

0.1795

− 0.046 (− 0.191–0.099)

0.5347

− 0.152 (− 0.288 − (− 0.016))

0.0288

Age, years

− 0.003 (− 0.008–0.002)

0.2344

0.003 (0.0002–0.007)

0.0369

0.009 (0.001–0.016)

0.0195

0.006 (− 0.0009 to 0.013)

0.0875

HBsAg, log10 IU/mL

0.237 (0.212–0.262)

< 0.0001

0.245 (0.217–0.273)

< 0.0001

− 0.024 (− 0.081–0.033)

0.4129

− 0.058 (− 0.118–0.002)

0.0591

HBV DNA, log10 copies/mL

0.070 (0.046–0.093)

< 0.0001

− 0.006 (− 0.027 to 0.014)

0.5507

0.065 (0.028–0.101)

0.0006

0.021 (− 0.023 to 0.064)

0.3542

ALT, log10 U/L

0.102 (0.018–0.186)

0.0176

0.025 (− 0.038–0.089)

0.4319

0.400 (0.285–0.515)

< 0.0001

0.404 (0.267–0.540)

< 0.0001

  1. ALT alanine aminotransferase, CGMH-LB Chang Gung Memorial Hospital, Linkou Branch, CGMH-KB Chang Gung Memorial Hospital, Kaohsiung Branch, CI confidence interval, HBV hepatitis B virus, HBeAg hepatitis B e antigen, HBsAg hepatitis B surface antigen, IQR interquartile range, SD standard deviation, sPD-1 soluble programmed cell death protein 1