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Table 1 Performance characteristics of the in-house SARS-CoV-2 N-protein based ELISA

From: Sensitive and specific serological ELISA for the detection of SARS-CoV-2 infections

 

PCR

Symptom onset

PCR + symptom onset

Sensitivity

   

[+] 0–6 da

40.9% (20.7–63.7%)

0%

39.1% (19.7–61.5%)

[+] 7–13 db

86.4% (65.1–97.1%)

–

86.4% (65.1–97.1%)

[+] 14–55 dc

100% (89.2–100%)

79.4% (62.1–91.3%)

89.7% (79.9–95.8%)

Specificity

   

SARS–CoV–2 [–]d

–

–

99.3% (98.8–99.68%)

  1. Confidence intervals (95%) are given in brackets. The median of days after symptom onset/PCR for the group [+] 14–55 d was 33 d
  2. aSample cohort consisted of 23 RT-PCR confirmed SARS-CoV-2 infections including one with documented symptom onset
  3. bSample cohort consisted of 22 RT-PCR confirmed SARS-CoV-2 infections
  4. cSample cohort consisted of 68 RT-PCR confirmed SARS-CoV-2 infections including 34 with documented symptom onsets
  5. dSample cohort consisted of 1500 control sera collected before 2015
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Virology Journal

ISSN: 1743-422X