Fig. 5

Transcripts with altered coding potential. a Transcript isoforms with TSSs located within the canonical ORFs of the host genes in many cases contain in-frame truncated ORFs. The gray histogram illustrates the CAGE-Seq data generated by O ‘Grady and colleagues [26]. b Alternative splicing of the BZLF1 transcripts results in nonsense termination of the ORFs highlighted by the orange wide rectangles and in deletion of the exon in BZLT51 transcript that does not cause frameshift but an ORF with deleted nucleotides. c Splicing of the unspliced BZLT10 leads to the deletion of a large portion of the ORF and results in an intergenic stop codon (first exon shown by green, while the second exon shown by the orange wide rectangles). This figure shows examples, and not a summary of all data