Serotype-dependent recombinant adeno-associated vector (AAV) infection of Epstein–Barr virus-positive B-cells, towards recombinant AAV-based therapy of focal EBV + lymphoproliferative disorders

Table 2 Sources of Human B-cells

Cell type	Source	Description
Primary cells
Primary B-cell EBV-	New England Organ Bank	Human spleen
B-LCL
Newly EBV-infected primary B-cell	In vitro infection with B95-8 virus strain	Human spleen
Standard B-lymphoblastoid cell line
B95-8	ATCC-CRL-1612	Marmoset B-cells, immortalized with the prototype B95-8 EBV strain
EBV + Burkitt lymphoma lines
P3HR1	ATCC-HTB-62	Burkitt lymphoma derived from Jijoye Burkitt lymphoma
Daudi	ATCC-CCL-213	Burkitt lymphoma
Raji	ATCC-CCL-86	Burkitt lymphoma
EBV-Burkitt lymphoma lines
Ramos	ATCC CRL-1596	Burkitt lymphoma
BL41	ATCC-ACC160	Burkitt lymphoma
In vitro-infected EBV + Burkitt’s lymphoma lines
Ramos/B95-8	Fred Wang and Elliot Kieff Harvard University	In vitro EBV-infected Burkitt lymphoma line
BL41/B95-8	Fred Wang and Elliot Kieff Harvard University	In vitro EBV-infected Burkitt lymphoma line

Cell lines included two EBV−, five EBV+ Burkitt lymphoma lines, and two EBV-immortalized lymphoblastoid cell lines (LCLs), as well as primary B-cells
ATCC American Type Culture Collection (Manassas, Virginia)

ISSN: 1743-422X