Fig. 1

Reproduced with permission from Ref. [11]
PRRS genome and replication cycle. The genomic replication cycle commences with the translation of polyproteins PP1a and PP1ab. These polyproteins are cleaved into the 14 nsps, which form the replication and transcription complex (RTC). The RTC transcribes the RNA minus strand and subgenomic mRNA (sgRNA).