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Fig. 4 | Virology Journal

Fig. 4

From: GATA binding protein 4 promotes the expression and transcription of hepatitis B virus by facilitating hepatocyte nuclear factor 4 alpha in vitro

Fig. 4

HBV had no significant effect on GATA4 in HBV cccDNA cell model and mouse model. HepG2 cells were transfected with HBV cccDNA (500 ng/mL) for 48 h. a Relative mRNA of GATA4 in cells detected via RT-qPCR, β-actin was used as the internal control. P = 0.46 vs. control group. b Analysis of HBV DNA copies in liver of HBV CBA/CaJ mouse models determined by qPCR, the average copy numbers of HBV DNA are 4.2 × 104 copies and 5.7 × 104 copies at 4 weeks and 24 weeks, respectively. c Relative mRNA of GATA4 in liver of HBV CBA/CaJ mouse models (n = 3) detected via RT-qPCR, β-actin was used as the internal control. P = 0.91 or P = 0.26 vs. control group

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Virology Journal

ISSN: 1743-422X