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Table 1 Laboratory results, hepatitis tests, serological tests, and single nucleotide polymorphism genotype and phenotype

From: Case report: hepatitis in a child infected with SARS-CoV-2 presenting toll-like receptor 7 Gln11Leu single nucleotide polymorphism

Tests (units)/dates

08/24–26

09/02

11/18

Reference range

Hemoglobin (g/dL)

12.8

10.7

12.9

11.5–13.5

Leukocytes (cells/mm3)

10,030

8450

6170

5000–14,500

Platelets (cells/mm3)

369,000

589,000

432,000

150,000–400,000

C-Reactive protein (mg/L)

233

62

< 12

Aspartate aminotransferase (IU/L)

326

48

33

10–47

Alanine aminotransferase (IU/L)

234

49

19

24–49

Bilirubin/direct bilirubin (mg/dL)

4.4/4.0

0.9/0.6

0/0

≤ 1.2/≤ 0.4

Gamma-glutamyl transferase (IU/L)

833

239

22

< 30

Alkaline phosphatase (IU/L)

770

329

253

142–335

Albumin (g/dL)

3.9

3.9

4.3

2.9–4.7

Activated partial thromboplastin time (s)

69

62

77

25–35

International normalized ratio (INR)

1.28

1.38

1.3

0.87–1.2

D-dimer (mcg/mL)

1.46

1.83

≤ 0.5

α1-Antitrypsin (mg/L)

293

78–200

Ceruloplasmin (mg/dL)

36

20–60

Antinuclear antibody

1:80

NR

Anti-smooth muscle

NR

NR

Seric copper (mcg/dL)

177

90–190

Urinary copper (mcg/24 hs)

11

≤ 60

Anti-liver kidney microsome type 1

NR

NR

SARS-CoV-2 IgG/IgA/IgM

P/P/P

N

VDRL

N

N

RTqPCR influenza A, B; RSV and SARS-CoV2

N/N/N

N/N/N

Anti-human immunodeficiency virus 1,2

N

N

Anti-hepatitis A virus/C virus

N/N

N/N

Anti-hepatitis E IgM

N

N

Hepatitis B, HBsAg, anti-HBc-IgM

N/N/N

N/N/N

Anti-human herpes virus IgM

N

N

Anti-cytomegalovirus IgG/IgM

P/N

N

Anti-Epstein–Barr virus IgG/IgM

P/N

N

TLR-7 T/T (A/A)

M

TLR-3 C/C (C/C)

NH

-

TIRAP C/C (C/C)

NH

MCP-1 A/A (A/A)

NH

OAS-3 C/C (C/C)

NH

  1. Bold means alterations in tests
  2. MCP-1 monocyte chemoattractant protein 1, M mutated, non-functional, NH normal homozygote, OAS-3 2′-5′-oligoadenylate synthetase 3, SARS-CoV-2 severe acute respiratory syndrome coronavirus type 2, SNP single nucleotide polymorphism, RSV respiratory syncytial virus, TIRAP toll-interleukin 1 receptor domain-containing adapter protein, TLR-3 toll like receptor 3, TLR-7 toll like receptor 7, VDRL Venereal Disease Research Laboratory, P positive, N negative, NR non-reactive, not done