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Table 1 Demographic characteristics and factors associated with drug resistance

From: Transmitted drug resistance and transmission clusters among HIV-1 treatment-naïve patients in Guangdong, China: a cross-sectional study

Variable Number TDR, N (%) Crude OR (95% CI) P-value Adjusted OR(95% CI) P-value
Total 2368 52 (2.2)     
Age (years)       
< 35 1097 25 (2.3) 1.000    
35–49 737 15 (2.0) 0.891 (0.466–1.701) 0.726   
≥ 50 534 12 (2.2) 0.986 (0.491–1.978) 0.968   
Marital status       
Unmarried 1096 22 (2.0) 1.000    
Married 875 16 (1.8) 0.909 (0.475–1.742) 0.774   
Divorce or widow 289 10 (3.5) 1.750 (0.819–3.738) 0.149   
Unknown 108 4 (3.7) 1.878 (0.635–5.552) 0.255   
Education       
Primary and below 330 4 (1.2) 1.000    
Junior high school 823 17 (2.1) 1.719 (0.574–5.147) 0.333   
Senior high school 551 12 (2.2) 1.814 (0.580–5.673) 0.306   
College and Above 586 16 (2.7) 2.288 (0.758–6.901) 0.142   
Unknown 78 3 (3.8) 3.260 (0.715–14.873) 0.127   
Ethnicity       
Han 2202 48 (2.2) 1.000    
Ethnic minorities 88 1 (1.1) 0.516 (0.070–3.780) 0.515   
Unknown 78 3 (3.8) 1.795 (0.547–5.894) 0.335   
Transmission route       
HET 1004 19 (1.9) 1.000    
MSM 1107 26 (2.3) 1.247 (0.686–2.267) 0.469   
IDU 80 1 (1.3) 0.656 (0.087–4.996) 0.683   
Other 177 6 (3.4) 1.819 (0.716–4.620) 0.208   
CD4+ T cell count(cells/mm3)       
< 200 895 15 (1.7) 1.000   1.000  
200–499 1220 23 (1.9) 1.127 (0.585–2.173) 0.721   
≥ 500 253 14 (5.5) 3.437 (1.636–7.219) 0.001 4.062 (1.904–8.668) < 0.001
Genotype       
CRF01_AE 842 24 (2.9) 1.000   1.000  
CRF07_BC 850 10 (1.2) 0.406 (0.193–0.854) 0.017 0.360 (0.170–0.764) 0.008
CRF08_BC 66 2 (3.0) 1.065 (0.246–4.608) 0.933   
CRF55_01B 244 5 (2.0) 0.713 (0.269–1.889) 0.496   
CRF59_01B 53 1 (1.9) 0.655 (0.087–4.941) 0.682   
Subtype B 70 3 (4.3) 1.526 (0.448–5.199) 0.499   
Othera 243 7 (2.9) 1.011 (0.430–2.375) 0.980