Table 1 Demographic characteristics and factors associated with drug resistance
Variable | Number | TDR, N (%) | Crude OR (95% CI) | P-value | Adjusted OR(95% CI) | P-value |
|---|---|---|---|---|---|---|
Total | 2368 | 52 (2.2) | ||||
Age (years) | ||||||
< 35 | 1097 | 25 (2.3) | 1.000 | |||
35–49 | 737 | 15 (2.0) | 0.891 (0.466–1.701) | 0.726 | ||
≥ 50 | 534 | 12 (2.2) | 0.986 (0.491–1.978) | 0.968 | ||
Marital status | ||||||
Unmarried | 1096 | 22 (2.0) | 1.000 | |||
Married | 875 | 16 (1.8) | 0.909 (0.475–1.742) | 0.774 | ||
Divorce or widow | 289 | 10 (3.5) | 1.750 (0.819–3.738) | 0.149 | ||
Unknown | 108 | 4 (3.7) | 1.878 (0.635–5.552) | 0.255 | ||
Education | ||||||
Primary and below | 330 | 4 (1.2) | 1.000 | |||
Junior high school | 823 | 17 (2.1) | 1.719 (0.574–5.147) | 0.333 | ||
Senior high school | 551 | 12 (2.2) | 1.814 (0.580–5.673) | 0.306 | ||
College and Above | 586 | 16 (2.7) | 2.288 (0.758–6.901) | 0.142 | ||
Unknown | 78 | 3 (3.8) | 3.260 (0.715–14.873) | 0.127 | ||
Ethnicity | ||||||
Han | 2202 | 48 (2.2) | 1.000 | |||
Ethnic minorities | 88 | 1 (1.1) | 0.516 (0.070–3.780) | 0.515 | ||
Unknown | 78 | 3 (3.8) | 1.795 (0.547–5.894) | 0.335 | ||
Transmission route | ||||||
HET | 1004 | 19 (1.9) | 1.000 | |||
MSM | 1107 | 26 (2.3) | 1.247 (0.686–2.267) | 0.469 | ||
IDU | 80 | 1 (1.3) | 0.656 (0.087–4.996) | 0.683 | ||
Other | 177 | 6 (3.4) | 1.819 (0.716–4.620) | 0.208 | ||
CD4+ T cell count(cells/mm3) | ||||||
< 200 | 895 | 15 (1.7) | 1.000 | 1.000 | ||
200–499 | 1220 | 23 (1.9) | 1.127 (0.585–2.173) | 0.721 | ||
≥ 500 | 253 | 14 (5.5) | 3.437 (1.636–7.219) | 0.001 | 4.062 (1.904–8.668) | < 0.001 |
Genotype | ||||||
CRF01_AE | 842 | 24 (2.9) | 1.000 | 1.000 | ||
CRF07_BC | 850 | 10 (1.2) | 0.406 (0.193–0.854) | 0.017 | 0.360 (0.170–0.764) | 0.008 |
CRF08_BC | 66 | 2 (3.0) | 1.065 (0.246–4.608) | 0.933 | ||
CRF55_01B | 244 | 5 (2.0) | 0.713 (0.269–1.889) | 0.496 | ||
CRF59_01B | 53 | 1 (1.9) | 0.655 (0.087–4.941) | 0.682 | ||
Subtype B | 70 | 3 (4.3) | 1.526 (0.448–5.199) | 0.499 | ||
Othera | 243 | 7 (2.9) | 1.011 (0.430–2.375) | 0.980 |