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Table 4 Cox regression analysis of factors for the clearance of SARS-CoV-2 using date of initial symptoms as the start of follow-up

From: Clinical and virological course of patients with coronavirus disease 2019 in Jiangsu province, China: a retrospective, multi-center cohort study

Variables Univariate Multivariate  
HR (95% CI) P value HR (95% CI) P value
Age (year)     
 ≤ 60 Reference    
 > 60 0.610 (0.450, 0.826) 0.001 0.643 (0.454, 0.911) 0.013
Sex     
 Female Reference    
 Male 0.992 (0.798, 1.233) 0.942 0.916 (0.721, 1.165) 0.475
BMI (kg/m2)     
 < 28 Reference    
 ≥ 28 1.049 (0.751, 1.466) 0.778 1.155 (0.817, 1.631) 0.415
Hypertension     
 No Reference    
 Yes 0.743 (0.549, 1.006) 0.055 0.905 (0.646, 1.269) 0.564
Diabetes     
 No Reference    
 Yes 0.764 (0.515, 1.134) 0.181 0.869 (0.561, 1.346) 0.528
Lymphocytes     
 No decreased Reference    
 Decreased 0.885 (0.698, 1.123) 0.316   
ALT (U/L)     
 ≤ 40 Reference    
 > 40 1.057 (0.801, 1.396) 0.696   
LDH (U/L)     
 ≤ 250 Reference    
 > 250 0.870 (0.697, 1.086) 0.217 0.935 (0.722, 1.210) 0.607
ALB (g/L)     
 > 35 Reference    
 ≤ 35 0.774 (0.557, 1.075) 0.126   
D-dimer (mg/L)     
 ≤ 0.5 Reference    
 > 0.5 0.857 (0.625, 1.176) 0.340   
Atomized inhalation of interferon α-2b     
 No Reference    
 Yes 1.355 (1.088, 1.688) 0.007 1.357 (1.050, 1.755) 0.020
Lopinavir/ritonavir treatment     
No Reference    
Yes 0.993 (0.771, 1.279) 0.957   
  1. PCR polymerase chain reaction, ALT alanine transaminase, LDH lactate dehydrogenase, ALB albumin