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Table 4 Cox regression analysis of factors for the clearance of SARS-CoV-2 using date of initial symptoms as the start of follow-up

From: Clinical and virological course of patients with coronavirus disease 2019 in Jiangsu province, China: a retrospective, multi-center cohort study

Variables

Univariate

Multivariate

 

HR (95% CI)

P value

HR (95% CI)

P value

Age (year)

    

 ≤ 60

Reference

   

 > 60

0.610 (0.450, 0.826)

0.001

0.643 (0.454, 0.911)

0.013

Sex

    

 Female

Reference

   

 Male

0.992 (0.798, 1.233)

0.942

0.916 (0.721, 1.165)

0.475

BMI (kg/m2)

    

 < 28

Reference

   

 ≥ 28

1.049 (0.751, 1.466)

0.778

1.155 (0.817, 1.631)

0.415

Hypertension

    

 No

Reference

   

 Yes

0.743 (0.549, 1.006)

0.055

0.905 (0.646, 1.269)

0.564

Diabetes

    

 No

Reference

   

 Yes

0.764 (0.515, 1.134)

0.181

0.869 (0.561, 1.346)

0.528

Lymphocytes

    

 No decreased

Reference

   

 Decreased

0.885 (0.698, 1.123)

0.316

  

ALT (U/L)

    

 ≤ 40

Reference

   

 > 40

1.057 (0.801, 1.396)

0.696

  

LDH (U/L)

    

 ≤ 250

Reference

   

 > 250

0.870 (0.697, 1.086)

0.217

0.935 (0.722, 1.210)

0.607

ALB (g/L)

    

 > 35

Reference

   

 ≤ 35

0.774 (0.557, 1.075)

0.126

  

D-dimer (mg/L)

    

 ≤ 0.5

Reference

   

 > 0.5

0.857 (0.625, 1.176)

0.340

  

Atomized inhalation of interferon α-2b

    

 No

Reference

   

 Yes

1.355 (1.088, 1.688)

0.007

1.357 (1.050, 1.755)

0.020

Lopinavir/ritonavir treatment

    

No

Reference

   

Yes

0.993 (0.771, 1.279)

0.957

  
  1. PCR polymerase chain reaction, ALT alanine transaminase, LDH lactate dehydrogenase, ALB albumin
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Virology Journal

ISSN: 1743-422X