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Fig. 2 | Virology Journal

Fig. 2

From: Zoonotic vaccinia virus strains belonging to different genetic clades exhibit immunomodulation abilities that are proportional to their virulence

Fig. 2

Body weight of BALB/c mice uninfected or infected with VACV-BR. Groups of mice (n = 5) were inoculated with PBS or 104, 105, 106 PFU of PSTV (A), GP1V (B) or VACV-WR (C) by the intranasal route. Panel D represents the comparative weight loss in animals infected with 106 PFU of each one of the three viral samples. The mice’s weight was determined daily and those that lost more than 30% of their initial weight were euthanized. The percentages of median weight relative to their initial weight were plotted. The error bars indicate the standard deviations. Significance variations were calculated using the Two-way ANOVA post hoc Bonferroni with statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001

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