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Table 2 Nucleotide differences between TB40/EF and TB40/EE within coding regions

From: Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells

Gene

Protein

Position*

Sequence

Consequence

Prevalence (%)†

TB40/EF

TB40/EE

UL26

UL26

32,663§

C

E98

47

0

   

T

K98

53

100

UL69

UL69

100,074

G

H492

66

48

   

C

Q492

44

52

UL122

IE2

171,008

C

D390

95

13

   

G

H390

5

87

UL128

UL128

175,937§

A

changes stop codon to Leu

30

0

   

C

wild-type

70

100

  

176,044

TC

deletion introduces a frameshift after codon 135

56

0

    

wild-type

44

100

UL130

UL130

176,753§

G

S207, disrupts disulfide bond with C176

9

0

   

C

C207, forms disulfide bond with C176

91

100

UL141

UL141

184,933

 

wild-type

56

31

   

TA

insertion introduces a frameshift after codon 63

44

69

US28

US28

227,251§

T

C320

12

0

   

G

W320

88

100

  1. *Coordinates refer to TB40/EF
  2. †Percentage of reads containing the variant
  3. §The consensus sequences for TB40/EF and TB40/EE are identical at this locus