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Table 2 Nucleotide differences between TB40/EF and TB40/EE within coding regions

From: Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells

Gene Protein Position* Sequence Consequence Prevalence (%)†
TB40/EF TB40/EE
UL26 UL26 32,663§ C E98 47 0
    T K98 53 100
UL69 UL69 100,074 G H492 66 48
    C Q492 44 52
UL122 IE2 171,008 C D390 95 13
    G H390 5 87
UL128 UL128 175,937§ A changes stop codon to Leu 30 0
    C wild-type 70 100
   176,044 TC deletion introduces a frameshift after codon 135 56 0
     wild-type 44 100
UL130 UL130 176,753§ G S207, disrupts disulfide bond with C176 9 0
    C C207, forms disulfide bond with C176 91 100
UL141 UL141 184,933   wild-type 56 31
    TA insertion introduces a frameshift after codon 63 44 69
US28 US28 227,251§ T C320 12 0
    G W320 88 100
  1. *Coordinates refer to TB40/EF
  2. †Percentage of reads containing the variant
  3. §The consensus sequences for TB40/EF and TB40/EE are identical at this locus
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Virology Journal

ISSN: 1743-422X