Role of antenatal plasma cytomegalovirus DNA levels on pregnancy outcome and HIV-1 vertical transmission among mothers in the University of Zimbabwe birth cohort study (UZBCS)

Table 3 Predictors of maternal HIV-1-RNA load

	Dependent variable: maternal HIV-RNA load (10,000 copies/mL)
	Without variable elimination	With variable elimination
Linear regression results—linear coefficients for antenatal HIV-RNA load
Maternal CMV-DNA > 50 copies/mL (yes/no)	4.15 (CI 1.57–6.74) ***	4.07 (CI 1.53–6.65) ***
Years with HIV diagnosis	− 0.10 (CI − 0.47–0.27)
On cART (yes/no)	− 3.32 (CI − 6.05-(-)0.60) **	− 3.58 (CI − 6.04-(-)1.11)***
Maternal age (years)	< 0.01 (CI − 0.19–0.19)

Linear regression showing the association of different variables with maternal HIV-1-RNA load in HIV-infected but non-transmitting mothers. Results are presented as linear coefficients per 10.000 HIV copies/mL; p-values are indicated as follows: *p < 0.1, **p < 0.05, ***p < 0.01. 118 mothers were analysed (excluded: 2 due to missing data, 4 stillbirths and 11 MTCT cases)
CI: 95% confidence interval, CMV: cytomegalovirus, cART: combination anti-retroviral treatment, HIV: human immunodeficiency virus

ISSN: 1743-422X