Role of antenatal plasma cytomegalovirus DNA levels on pregnancy outcome and HIV-1 vertical transmission among mothers in the University of Zimbabwe birth cohort study (UZBCS)

Table 2 Predictors of HIV-MTCT

	Dependent variable: HIV transmission (yes/no)
	Without variable elimination	With variable elimination
Logistic regression results—odds ratios for vertical HIV transmission risk
Maternal CMV-DNA of > 50 copies/mL (yes/no)	3.62 (CI 0.81–16.29) *	4.02 (CI 1.09–15.30) **
Maternal HIV-RNA load (per 1000 copies/mL)	1.05 (CI 0.99–1.14)
Years with HIV diagnosis	1.09 (CI 0.93–1.26)	1.12 (CI 0.97–1.30) *
On cART (yes/no)	1.08 (CI 0.96–1.22)
Maternal age (years)	3.81 (CI 0.39–167.23)

Logistic regression showing the association of different variables with MTCT in HIV-infected mothers with live infants. Results are presented as odds ratios; p-values are indicated as follows: *p < 0.1, **p < 0.05, ***p < 0.01. 128 infants were analysed (excluded: 2 due to missing data, 4 stillbirths)
CI: 95% confidence interval, CMV: cytomegalovirus, cART: combination anti-retroviral treatment, HIV: human immunodeficiency virus

ISSN: 1743-422X