Characterization of a recombinant pseudorabies virus expressing porcine parvovirus VP2 protein and porcine IL-6

Table 2 PRV-specific neutralizing antibody (NA) and PPV-specific HI antibody (Log ₂)^a levels in mice

Group	Weeks post the first vaccination
	0		2		4		6		8
	NA	HI	NA	HI	NA	HI	NA	HI	NA	HI
rPRV-VP2-IL6	-^b	0	1:2	2.5 ± 0.2^{* c}	1:8	4.1 ± 0.3^*	1:32	5.3 ± 0.2^*	1:128	6.9 ± 0.3^*
rPRV-VP2-EGFP	–	0	1:2	2.0 ± 0.2^*	1:8	3.9 ± 0.2^*	1:32	5.0 ± 0.3^*	1:64	6.5 ± 0.2^*
PPV vaccine	–	0	–	4.0 ± 0.3^*	–	6.3 ± 0.3^*	–	5.6 ± 0.2^*	–	7.6 ± 0.3^*
PRV HB98	–	0	1:2	0	1:8	0	1:32	0	1:128	0
DMEM	–	0	–	0	–	0	–	0	–	0

^aValues are expressed as mean HI antibody titer ± standard error
^bNA titers <2
^cStatistically significant differences (P < 0.05) are indicated by*(compared with compared with PRV HB98 or DMEM)

ISSN: 1743-422X